Reverse Engineering Nature towards Programing Protein Molecules

Speaker:Gevorg Grigoryan
Date: Monday, September 19, 2016
Time: 11:30am - 12:30pm
Location: 103 Gross Hall, Duke

Abstract

The fundamental question driving our work is how protein sequence encodes specific structure. We are interested in just about everything having to do with this: how to understand sequence-to-structure mapping, how to predict structure from sequence, and how to model this mapping well enough to enable the robust design of novel proteins with desired functions. We employ a cycle between computational modeling and prediction (using either first-principles or empirical approaches) and experimental measurement and validation to study these problems.

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